Breast Cancer

Trial Add-Aspirin Trial
Cancer Type Bowel Cancer, Breast Cancer, Oesophageal Cancer, Prostate Cancer, Stomach Cancer, and Non-specific
Hospital(s) Belfast City Hospital and Craigavon Hospital
Information

A Phase III, Double-Blind, Placebo-Controlled Randomised Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival after Primary Therapy in Common Non-Metastatic Solid Tumours

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Trial ARCS-Multi
Cancer Type Breast Cancer, Lung Cancer, Stomach Cancer, and Non-specific
Hospital(s) Belfast City Hospital
Information

Phase 1b multi-indication study of anetumab ravtansine (BAY 94-9343) in patients with mesothelin expressing advanced or recurrent malignancies

Trial CIBRAC
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Chemoprevention in BRCA1 Mutation Carriers – a Proof of Concept Study

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Trial CORE
Cancer Type Breast Cancer, Lung Cancer, Prostate Cancer, and Non-specific
Hospital(s) Belfast City Hospital
Information

A Randomised Trial Of Conventional Care Versus Radioablation (Stereotactic Body Radiotherapy) For Extracranial Oligometastases

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Trial HORIZONS
Cancer Type Breast Cancer, Cervical Cancer, Endometrial (womb) Cancer, Haematological Cancers, Ovarian Cancer, Non-specific, Lymphoma, and Vulval Cancer
Hospital(s) Antrim Hospital and Ulster Hospital
Information

A cohort study to explore recovery of health and well-being in adults diagnosed with cancer

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Trial LORIS
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital and Ulster Hospital
Information

A phase III trial of surgery versus active monitoring for low risk Ductal Carcinoma in Situ (DCIS)

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Trial Olympia
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

A randomised, double-blind, parallel group, placebo-controlled multi-centre Phase III study to assess the efficacy and safety of olaparib versus placebo as adjuvant treatment in patients with germline BRCA1/2 mutations and high risk HER2 negative primary breast cancer who have completed definitive local treatment and neoadjuvant or adjuvant chemotherapy

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Trial OPTIMA
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital and Ulster Hospital
Information

Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis

Trial PIONEER (Breast cancer)
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Randomised Phase II clinical trial PIONEER- A Pre-operative wIndOw study of Letrozole plus PR agonist (Megestrol Acetate) versus Letrozole aloNE in post-menopausal patients with ER-positive breast cancer

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Trial POSNOC
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy. A randomised controlled trial of axillary treatment in women with early stage breast cancer who have metastases in one or two sentinel nodes

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